Xofigo prostate cancer1/12/2024 ![]() Joyce comments: "Some patients may be making profound personal sacrifices in order remain adherent with their prostate cancer treatment, which may have a significant impact on the quality of life that we hope to prolong with these treatments. "Patients are often unable to meet the high treatment initiation costs without some type of financial assistance program or subsidy," the researchers write.ĭr. Patients with high financial toxicity were also more likely to use financial assistance programs: 32%, compared to 12% of those with low financial toxicity. More than half of patients with high financial toxicity reported difficulty paying bills-and patients in this group were more likely to have delays in starting cancer treatment. "Notably, very few patients reported only partially filling medications or stopping medications altogether due to cost," the researchers write. ![]() They were more likely to decrease spending on basic goods and leisure activities, to use their savings to pay for medical care, to delay filling prescriptions, and to borrow money to pay for their care. ![]() Patients experiencing high financial toxicity coped in varied ways. Not surprisingly, income was a significant factor: risk of financial toxicity was nine times lower for patients with annual incomes of $100,000, compared to incomes under $20,000. For patients who were married (or had a non-married partner), financial toxicity risk was nearly four times lower than for those who were unmarried, widowed, or divorced. Older patients had lower financial toxicity, as each additional year of age was associated with a 25% reduction in risk. Several patient characteristics were associated with higher or lower risks of financial toxicity. Patients may make 'profound personal sacrifices' to remain compliant with prostate cancer treatments The impact was "more profound" among patients with high financial toxicity, with 89% percent reporting financial hardship. Overall, 54% of patients said they experienced at least some level of financial hardship related to their cancer treatment. The analysis included responses from 281 patients, median age 69 years.īased on the study questionnaire, 79 patients were classified as having high financial toxicity. Joyce and Boorjian and colleagues assessed the rate of financial toxicity and the related patient characteristics and coping strategies among patients being treated for metastatic prostate cancer. ![]() Previous reports suggest that up to half of cancer survivors are affected by financial toxicity, which has been linked to increased rates of adverse treatment outcomes.ĭrs. Financial toxicity-which has been defined as "the harm to patients that results from treatment costs"-has become recognized as important patient-centered outcome. ![]() The researchers administered a validated questionnaire concerning financial toxicity to all patients seen at their advanced prostate cancer clinic over a three-month period. New data on financial toxicity rates, risk factors, and coping strategies "Simply asking patients whether they are following their suggested treatments is not sufficient to screen for financial toxicity." "Our most significant finding may be that patients experience financial toxicity despite their ability to remain compliant with treatment," says lead author Daniel D. Boorjian, MD, of Mayo Clinic, Rochester, Minn. "Our findings help in understanding the rates of and risk factors for financial toxicity among patients with advanced prostate cancer, along with the coping mechanisms, including the impact on personal spending, experienced by those reporting higher levels of financial toxicity," comments senior author Stephen A. ![]()
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